Waterloo researchers study coronavirus structure to help design drugs for current and future pandemics
Thursday, June 10, 2021 Professors Aravindhan Ganesan (Pharmacy, left) and Subha Kalyaanamoorthy (Chemistry, right) use drug design methods to target the molecular machinery that supports COVID-19 replication To effectively design treatment for a virus, scientists must first understand its structure and dynamics at the molecular level. COVID-19, which is caused by the SARS-CoV-2 virus, […]
June 10, 2021
Repurposing potential drug candidates for the treatment of COVID-19
Summary The main protease (Mpro) in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for the coronavirus disease (COVID-19), has emerged as a promising drug target. The scientific community has produced a large number of crystallographic structures of the protease, which mediates viral replication and transcription. These structures report several fragments with varied chemotypes […]
May 6, 2020